They are a unique combination — august publications in science and medicine that  harken back for centuries yet now inform 21st century practitioners about the latest advances in their fields. And now these leading scientific journals say the present moment  forces them to abandon their prized political neutrality to oppose the science denialism of the incumbent leader of the free world.

This is an unprecedented and uncomfortable development for the New England Journal of Medicine, Nature, Scientific American, and Lancet Oncology (a journal for cancer specialists). They have never taken a political stand of this kind in their histories, dating to 1812 for NEJM, 1845 for Scientific American, and 1869 for Nature.

Their editors say they would much prefer to stay out of presidential endorsements  and to keep their focus on publishing important, rigorous research and peer-reviewed information about advancements in the fields of science and medicine.